See also: Practice Locations for Online Booking
Prerequisites for Location support in Online Booking:
(Configure - > Practice Settings >
Enable Locations)
Configure > Online Appointments > Web Setup window >
Enable Location
On upgrade to EXACT v12.8:
Practices with multiple existing Locations will have those locations listed in the Web Setup, but without being configured or enabled.
Each Location is an Online Booking blank slate:
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Once they tick to Enable Locations, the pre-configured Locations appear in the Enable Locations dropdown list:

To configure Locations for Online Booking
(SEE ALSO: Configuring the online booking website)
NOTE: Once locations are enabled, until you define them, on logging into EXACT you will see this message:

Default Location for Providers and Patients who have none specified:
The top Location in the dropdown menu is used by EXACT as the preferred Location for those Providers and Patients who have not specifically been configured with a Location:

So, unless you assign New patients a Location, EXACT will assume this as their Location.
(You can independently set up a booking website for each of your created Locations):

SEE ALSO: Configuring the online booking website
Appearance options:
For example:

EXACT applies the following logic in using Preferred Locations versus other locations:
IMPORTANT: To use locations effectively, Providers and Patients should have Preferred Locations specified, and practitioners should habitually record Preferred Locations for new patients.
Online Booking Providers:
The Provider Details tab has a Pref Location field.
Patients who book online:
The Patient Details tab has a Pref Location field.
Combined Recalls:
For Combined Recalls, EXACT uses location options in this order:
Family Recalls:
For family recall, EXACT uses the main contact patient's location in this order:
Marketing Campaign:
For marketing campaigns EXACT uses locations in this order:
Appointment Workflow:
From EXACT v12.9 practitioners who log in to a Location and use the Appointment Workflow will see only that Location's patients on the Departure Task List (Exit Workflow). Patients who are booked for a different Location will not display.
Merge Fields for Preferred Location:
From EXACT v12.9 EXACT has merge fields specifically for using the Preferred Location in patient correspondence.
To set up Preferred Location for Providers

If you do not configure a Provider Preferred Location:
The top Location in the dropdown menu will be used by EXACT as the preferred Location for those Providers who have not specifically been configured with a Location:

If the Preferred Location is deleted from Locations setup:
In this situation EXACT will prompt you to update the Provider's Preferred Location.
To set up Preferred Location for Patients

If you do not configure a Patient Preferred Location:
The top Location in the dropdown menu will be used by EXACT as the preferred Location for those Patients who have not specifically been configured with a Location:

Location field in the Edit Appointment window
Each Edit Appointment window has the Location field situated just above the Planned Treatment window:

See also:
Configuring the online booking website
Rotas, Rosters, Blocks and Clinics
Configuring multiple Locations and Templates for Reputation Manager